CN: 32-1845/R
ISSN: 2095-6975
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MEI Xiao-Dan, CAO Yan-Feng, CHE Yan-Yun, LI Jing, SHANG Zhan-Peng, ZHAO Wen-Jing, QIAO Yan-Jiang, ZHANG Jia-Yu. Danshen: a phytochemical and pharmacological overview[J]. Chinese Journal of Natural Medicines, 2019, 17(1): 59-80

Danshen: a phytochemical and pharmacological overview

MEI Xiao-Dan1, CAO Yan-Feng1, CHE Yan-Yun2, LI Jing3, SHANG Zhan-Peng1, ZHAO Wen-Jing1, QIAO Yan-Jiang1, ZHANG Jia-Yu4
1 School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China;
2 College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China;
3 College of Basic Medicine, Jinzhou Medical University, Jinzhou 121001, China;
4 Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
Abstract:
Danshen, the dried root or rhizome of Salvia miltiorrhiza Bge., is a traditional and folk medicine in Asian countries, especially in China and Japan. In this review, we summarized the recent researches of Danshen in traditional uses and preparations, chemical constituents, pharmacological activities and side effects. A total of 201 compounds from Danshen have been reported, including lipophilic diterpenoids, water-soluble phenolic acids, and other constituents, which have showed various pharmacological activities, such as anti-inflammation, anti-oxidation, anti-tumor, anti-atherogenesis, and anti-diabetes. This article intends to provide novel insight information for further development of Danshen, which could be of great value to its improvement of utilization.
Key words:    Danshen    Traditional uses    Chemical constituents    Quality control    Pharmacological activities   
Received: 2018-10-17   Revised:
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Articles by MEI Xiao-Dan
Articles by CAO Yan-Feng
Articles by CHE Yan-Yun
Articles by LI Jing
Articles by SHANG Zhan-Peng
Articles by ZHAO Wen-Jing
Articles by QIAO Yan-Jiang
Articles by ZHANG Jia-Yu
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