CN: 32-1845/R
ISSN: 2095-6975
Cite this paper:
0
GAO Yuan, XIAO Wei, LIU Hong-Chun, WANG Jian-Rong, YAO Li-Gong, OUYANG Ping-Kai, WANG De-Cai, GUO Yue-Wei. Clavuridins A and B, two new trinor-guaiane sesquiterpenes isolated from the Xisha soft coral Clavularia viridis[J]. Chinese Journal of Natural Medicines, 2017, 15(11): 855-859

Clavuridins A and B, two new trinor-guaiane sesquiterpenes isolated from the Xisha soft coral Clavularia viridis

GAO Yuan1, XIAO Wei2, LIU Hong-Chun3, WANG Jian-Rong3, YAO Li-Gong3, OUYANG Ping-Kai1, WANG De-Cai1, GUO Yue-Wei3
1 College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China;
2 Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222002, China;
3 State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
Abstract:
In the present study, two new trinor-guaiane sesquiterpenes, named clavuridins B (1), and A (2), along with three known sesquiterpenes (3-5), were isolated from the Xisha soft coral Clavularia viridis. Their structures and absolute configurations were determined on the basis of spectroscopic analysis, X-ray diffraction analysis with Cu Kα radiation and by comparison with related model compounds. Compounds 1 and 3-5 were evaluated for their cytotoxic activity.
Key words:    Soft coral    Clavularia viridis    Trinor-guaiane sesquiterpene    Cytotoxic activity   
Received: 2017-04-08   Revised:
Tools
PDF (689 KB) Free
Print this page
Email this article to others
Authors
Articles by GAO Yuan
Articles by XIAO Wei
Articles by LIU Hong-Chun
Articles by WANG Jian-Rong
Articles by YAO Li-Gong
Articles by OUYANG Ping-Kai
Articles by WANG De-Cai
Articles by GUO Yue-Wei
References: