CN: 32-1845/R
ISSN: 2095-6975
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YAO Zhi-Hong, QIN Zi-Fei, DAI Yi, YAO Xin-Sheng. Phytochemistry and pharmacology of Allii Macrostemonis Bulbus, a traditional Chinese medicine[J]. Chinese Journal of Natural Medicines, 2016, 14(7): 481-498

Phytochemistry and pharmacology of Allii Macrostemonis Bulbus, a traditional Chinese medicine

YAO Zhi-Hong1, QIN Zi-Fei1, DAI Yi1, YAO Xin-Sheng1,2
1. College of Pharmacy, Jinan University, Guangzhou 510632, China;
2. State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau, China
Abstract:
Allii Macrostemonis Bulbus (Xiebai in Chinese), as a famous traditional Chinese medicine, has great medicinal and dietary values since ancient times. In China, the dry bulbs of Allium macrostemon and Allium chinense are both used as its original plants. Pharmacological studies have revealed that both of them could increase plasminogen activator activity and prolong the effect of coagulation to achieve antiplatelet aggregation which validates their traditional uses for the treatment of thoracic obstruction and cardialgia in clinics. Besides, several other significant activities, including lipid-lowering, anti-atherosclerosis, antitumor, antispasmodic, antibacterial, antioxidant, and insecticidal activities, have already been reported. The volatile oils, nitrogenous compounds, and steroidal saponins are the major beneficial compounds. Among them, steroidal saponins are considered as the characteristic constituents. In this review, the current information concerning the phytochemistry and pharmacology of Allii Macrostemonis Bulbus is summarized comprehensively. In addition, several research future perspectives are presented, especially the mechanism of bioactive components and fraction from the bulbs of Allium macrostemon and Allium chinense.
Key words:    Allii Macrostemonis Bulbus    Allium macrostemon    Allium chinense    Phytochemistry    Pharmacology    Future perspectives   
Received: 2015-12-29   Revised:
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Articles by YAO Zhi-Hong
Articles by QIN Zi-Fei
Articles by DAI Yi
Articles by YAO Xin-Sheng
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