CN: 32-1845/R
ISSN: 2095-6975
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CHEN Xiao-Peng, LI Wei, XIAO Xue-Feng, ZHANG Lan-Lan, LIU Chang-Xiao. Phytochemical and pharmacological studies on Radix Angelica sinensis[J]. Chinese Journal of Natural Medicines, 2013, 11(6): 577-587

Phytochemical and pharmacological studies on Radix Angelica sinensis

CHEN Xiao-Peng1,2,3, LI Wei3, XIAO Xue-Feng4, ZHANG Lan-Lan3, LIU Chang-Xiao2
1 School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China;
2 State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China;
3 Tasly R & D Institute, Tianjin Tasly Group Co., Ltd., Tianjin 300410, China;
4 Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Abstract:
The roots of Angelica sinensis(RAS),are a Chinese herbal medicine traditionally used in prescriptions for replenishing blood,treating abnormal menstruation,and other women's diseases.It has also been widely marketed as health food for women's care in Asia,and as a dietary supplement in Europe and America.RAS is well-known for its hematopoietic,antioxidant,and immunoregulatory activities.RAS also possesses anti-cancer,memory,radioprotective,and neuroprotective effects.Phytochemical investigations on this plant led to organic acids,phthalides,polysaccharides,and other metabiolites.Based on recent animal studies and clinical trials,RAS has been used in the treatment of gynecologic diseases,cardio-cerebrovascular disease,nervous system diseases,and nephrotic syndrome.In this review,the recent phytochemical and pharmacological studies,drug-drug interactions,clinical applications,and toxicity of RAS are summarized.
Key words:    Radix Angelica Sinensis    Chemical constituents    Pharmacological effect    Interactions    Clinical applications    Toxicity   
Received: 2013-02-20   Revised:
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Articles by CHEN Xiao-Peng
Articles by LI Wei
Articles by XIAO Xue-Feng
Articles by ZHANG Lan-Lan
Articles by LIU Chang-Xiao
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