CN: 32-1845/R
ISSN: 2095-6975
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MA Jian-Ping, GUO Zhi-Bing, JIN Ling, LI Ying-Dong. Phytochemical progress made in investigations of Angelica sinensis (Oliv.) Diels[J]. 中国天然药物英文, 2015, 13(4): 241-249

Phytochemical progress made in investigations of Angelica sinensis (Oliv.) Diels

MA Jian-Ping1, GUO Zhi-Bing1, JIN Ling2, LI Ying-Dong2
1 College of Life Science and Technology, Lanzhou University of Technology, Lanzhou 730050, China;
2 Department of Pharmacy, Gansu College of Traditional Chinese Medicine, Lanzhou 730000, China
摘要:
The phytochemical progress on Angelica sinensis (Oliv.) Diels over the past decades is summarized. Since 1970s, 165 chemical constituents, including phthalides, phenylpropanoids, terpenoids and essential oils, aromatic compounds, alkaloids, alkynes, sterols, fatty acids, and polysaccharides have been isolated or detected from the various parts of the title plant.
关键词:    Angelica sinensis    Chemical constituents    Phthalides    Phenylpropanoids    Terpenoids and essential oils    Aromatic compounds    Sterols    Fatty acids    Polysaccharides   
收稿日期: 2014-04-19
MA Jian-Ping
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参考文献:
[1] Sarker SD, Nahar L. Natural medicine:the genus Angelica[J]. Curr Med Chem, 2004, 11:1479-1500.
[2] Monograph:Angelica sinenesis (Dong Quai)[J]. Altern Med Rev, 2004, 9(4):429-433.
[3] Su ZY, Khor TO, Shu LM, et al. Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and radix Angelica sinensis via promoter CpG demethylation[J]. Chem Res Toxicol, 2013, 26(3):477-485.
[4] Tsai NM, Chen YL, Lee CC, et al. The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo[J]. J Neurochem, 2006, 99(4):1251-1262.
[5] Ho CC, Kumaran A, Hwang LS. Bio-assay guided isolation and identification of anti-Alzheimer active compounds from the root of Angelica sinensis[J]. Food Chem, 2009, 114:246-252.
[6] Fang L, Xiao XF, Liu CX, et al. Recent advances in studies on Angelica sinensis[J]. Chin Herb Meds, 2012, 4(1):12-25.
[7] Yang JY, Chen HH, Wu J, et al. Advances in studies on pharmacological functions of ligustilide and their mechanisms[J]. Chin Herb Meds, 2012, 4(1):26-32.
[8] Lin Z, Gu J, Xiu J, et al. Traditional Chinese medicine for senile dementia[J]. J Evid-Based Compl Alt Med, 2012:1-13.
[9] Hsien MT, Tsai FH, Lin YC, et al. Effects of ferulic acid on the impairment of inhibitory avoidance performance in rats[J]. Planta Med, 2002, 68(8):754-756.
[10] Chen QC, Lee JP, Jin WY, et al. Cytotoxic constituents from Angelicae sinensis radix[J]. Arch Pharm Res, 2007, 30(5):565-569.
[11] Deng SX, Chen SN, Yao P, et al. Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis[J]. J Nat Prod, 2006, 69(4):536-541.
[12] Lü JL, Duan JA, Tang YP, et al. Phthalide mono-and dimers from the radix of Angelica sinensis[J]. Biochem Syst Ecol, 2009, 37:405-411.
[13] Wang YL, Liang YZ, Chen BM, et al. LC-DAD-APCI-MSbased screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of Dang Gui[J]. Anal Bioanal Chem, 2005, 383(2):247-254.
[14] Li WD, Wu Y, Liu XD, et al. Isolation, identification and screen of lactone compounds from Angelica sinensis[J]. Chin Tradit Pat Med, 2011, 33(12):2114-2118.
[15] Chen YZ, Zhang HD. Analysis of the chemical ingredients of Angelica sinensis. Analysis of non-volatile constituents of roots[J]. Chem J Chin Univ, 1984, 5(4):515-520.
[16] Lu XH, Liang H, Zhao YY. Isolation and identification of the ligustilide compounds from the root of Angelica sinensis[J]. China J Chin Mat Med, 2003, 28(5):423-425.
[17] Lao SC, Li SP, Kan KKW, et al. Identification and quantification of 13 components in Angelica sinensis (Dang Gui) by gas chromatography-mass spectrometry coupled with pressurized liquid extraction[J]. Anal Chim Acta, 2004, 526(2):131-137.
[18] Lin M, Zhu GD, Sun QM, et al. Chemical studies of Angelica sinensis[J]. Acta Pharm Sin, 1979, 14(9):529-534.
[19] Wang HY, Chen RX, Xu HZ. Studies on chemical constituents of radix Angelicae sinensis[J]. China J Chin Mat Med, 1998, 23(3):167-169.
[20] Song QY, Fu YB, Liu J, et al. Chemical constituents from Angelica sinensis[J]. Chin Tradit Herb Drugs, 2011, 42(10):1900-1904.
[21] Lu XH, Zhang JJ, Liang H, et al. Chemical constituents of Angelica sinensis[J]. J Chin Pharm Sci, 2004, 13(1):1-3.
[22] Huang WH, Song CQ. Studies on the chemical constituents of Angelica sinensis[J]. Acta Pharm Sin, 2003, 38(9):680-683.
[23] Hu CY, Ding XL. Isolation and identification of lactone compounds from the essential oil of Angelica sinensis[J]. Chin Tradit Herb Drugs, 2004, 35(4):383-384.
[24] Deng SX, Chen SN, Lu J, et al. GABAergic phthalide dimers from Angelica sinensis (Oliv.) Diels[J]. Phytochem Anal, 2006, 17(6):398-405.
[25] Lu XH, Zhang JJ, Zhang XX, et al. Study on biligustilides from Angelica sinensis[J]. China J Chin Mat Med, 2008, 33(19):2196-2201.
[26] Li XN, Chen YY, Cheng DP, et al. Two phthalide dimers from the radix of Angelica sinensis[J]. Nat Prod Res, 2012, 26(19):1782-1786.
[27] Su DM, Yu SS, Qin HL. New dimeric phthalide derivative from Angelica sinensis[J]. Acta Pharm Sin, 2005, 40(2):141-144.
[28] Nguyen THV, Nguyen THA, Tran VS, et al. Studies on chemical composition of Angelica sinensis. Part VI-Angelicolide and three other compounds[J]. Tap Chi Hoa Hoc, 2005, 43(6):749-752.
[29] Chen YZ, Zhang HD, Chen NY, et al. Analysis of the chemical ingredients of Angelica sinensis. Structural elucidation of angelicide[J]. Chin Sci Bull, 1983, 19:1206-1207.
[30] Lin LZ, He XG, Lian LZ, et al. Liquid chromatographic-electrospray mass spectrometric study of the phthalides of Angelica sinensis and chemical changes of Z-ligustilide[J]. J Chromatogr A, 1998, 810:71-79.
[31] Jiang W, Wang CH, Wang ZT. Water-soluble chemical constituents of Angelica sinensis (Oliv.) Diels[J]. Chin Pharm J, 2010, 45(2):101-103.
[32] Xue WX, Hua YL, Guo YS, et al. Changes of composition in different parts of Angelica sinensis based on geoherbs[J]. J Gansu Agric Univ, 2012, 47(1):149-154.
[33] Zhao XJ, Wang HF, Zhao DQ, et al. Isolation and identification of the chemical constituents from roots of Angelica sinensis (Oliv.) Diels[J]. J Shenyang Pharm Univ, 2013, 30(3):182-185, 221.
[34] Zhou GS, Yang NY, Tang YP, et al. Chemical constituents from the aerial parts of Angelica sinensis and their bioactivities[J]. Chin J Nat Med, 2012, 10(4):295-298.
[35] Chen YZ, Chen NY, Ma XY, et al. Analysis of the ingredients of Angelica sinenesis. Identification of the volatile components from the roots of Angelica sinensis by capillary GC-MS[J]. Chem J Chin Univ, 1984, 5(1):125-128.
[36] Nguyen THV, Nguyen THA, Tran VS, et al. Chemical study of Angelica sinensis[J]. Tap Chi Hoa Hoc, 2005, 43(4):494-498.
[37] Chen F, Yao C. Advances in studies on chemical constituents of Angelica sinensis[J]. Chongqing J Res Chin Drugs Herbs, 2002, (1):49-53.
[38] Yang NY, Zhou GS, Tang YP, et al. Two new alpha-pinene derivatives from Angelica sinensis and their anticoagulative activities[J]. Fitoterapia, 2011, 82(4):692-695.
[39] Chen YZ, Li HQ, Chen NY, et al. Analysis of the volatile components from the leaves of Angelica sinensis by capillary GC-MS[J]. J Lanzhou Univ (Med Sci), 1985, 21(3):130-132.
[40] Liu GS, Lu FS. Chemical analysis of the essential oil from Angelica sinensis and TLC comparasion of its constituents with those from Levisticum officinale[J]. Chin Pharm J, 1979, 14(8):375-377.
[41] Liu LN, Mei QB, Cheng JF. Analysis of the chemical components of the essential oil from Angelica sinensis (Oliv.) Diels[J]. Chin Tradit Pat Med, 2005, 27(2):204-206.
[42] Yi LZ, Liang YZ, Wu H, et al. The analysis of radix Angelicae sinensis (Dang Gui)[J]. J Chromatgr A, 2009, 1216:1991-2001.
[43] Deng SX, Wang YH, Inui T, et al. Anti-TB polyynes from the roots of Angelica sinensis[J]. Phytother Res, 2008, 22:878-882.
[44] Yang NY, Jiang S, Shang EX, et al. A new phenylpentanamine alkaloid produced by an endophyte Bacillus subtilis isolated from Angelica sinensis[J]. J Chem Res, 2012, 36(11):647.
[45] Ou SY, Kwok KC. Ferulic acid:pharmaceutical functions, preparation and applications in foods[J]. J Sci Food Agric, 2004, 84:1261-1269.
[46] Yang TH, Jia M, Zhou SY, et al. Antivirus and immune enhancement activities of sulfated polysaccharide from Angelica sinensis[J]. Int J Biol Macromol, 2012, 50:768-772.
[47] Chen Y, Duan JA, Qian DW, et al. Assessment and comparison of immunoregulatory activity of four hydrosoluble fractions of Angelica sinensis in vitro on the peritoneal macrophages in ICR mice[J]. Int Immunopharmacol, 2010, 10:422-430.
[48] Ye YN, So HL, Liu ESL, et al. Effect of polysaccharides from Angelica sinensis on gastric ulcer healing[J]. Life Sci, 2003, 72:925-932.
[49] Shang P, Qian AR, Yang TH, et al. Experimental study of antitumor effects of polysaccharides from Angelica sinensis[J]. World J Gastroenterol, 2003, 9(9):1963-1967.
[50] Lee JG, Hsieh WT, Chen SU, et al. Hematopoietic and myeloprotective activities of an acidic Angelica sinensis polysaccharide on human CD34+ stem cells[J]. J Ethnopharmacol, 2012, 139:739-745.
[51] Cao W, Li XQ, Liu L, et al. Structural analysis of water-soluble glucans from the root of Angelica sinensis (Oliv.) Diels[J]. Carbohydr Res, 2006, 341:1870-1877.
[52] Cao W, Li XQ, Liu L, et al. Structure of an anti-tumor polysaccharide from Angelica sinensis (Oliv.) Diels[J]. Carbohydr Polym, 2006, 66:149-159.
[53] Zhou SY, Zhang BL, Liu XY, et al. A new natural Angelica polysaccharide based colon-specific drug delivery system[J]. J Pharm Sci, 2009, 98(12):4756-4768.
[54] Yang XB, Zhao Y, Zhou YJ, et al. Component and antioxidant properties of polysaccharide fractions isolated from Angelica sinensis (Oliv.) Diels[J]. Biol Pharm Bull, 2007, 30(10):1884-1890.
[55] Ai ST, Fan XD, Fan LF. Extraction and chemical characterization of Angelica sinensis polysaccharides and its antioxidant activity[J]. Carbohydr Polym, 2013, 94:731-736.
[56] Liu JY, Zhang Y, You RX, et al. Polysaccharide isolated from Angelica sinensis inhibits hepcidin expression in rats with iron deficiency anemia[J]. J Med Food, 2012, 15(10):923-929.
[57] Yang YQ, Chin A, Zhang LK, et al. The role of traditional Chinese medicines in osteogenesis and angiogenesis[J]. Phytother Res, 2014, 28(1):1-8.
[58] Li WD, Wu Y, Liu XD, et al. Antioxidant properties of cis-Z, Z'-3a.7a',7a.3a'-dihydroxy ligustilide on human umbilical vein endothelial cells in vitro[J]. Molecules, 2013, 18:520-534.
[59] Yang TH, Jia M, Zhou SY, et al. Antivirus and immune enhancement activities of sulfated polysaccharide from Angelica sinensis[J]. Int J Biol Macromol, 2012, 50:768-772.
[60] Zhang XY, Qiao H, Shi YB, et al. HPLC method with fluorescence detection for the determination of ligustilide in rat plasma and its pharmacokinetics[J]. Pharm Biol, 2014, 52(1):21-30.
[61] Yang YL, Yang T, Yang YH, et al. Determination of light toxic compound coumarin in enrichment Angelica pills and Angelica sinensis by ultra performance liquid chromatography[J]. Chin J Anal Chem, 2013, 41(11):1744-1748.
[62] Li Y, Wang SW, Tu HH, et al. Simultaneous quantification of six main active constituents in Chinese Angelica by high-performance liquid chromatography with photodiode array detector[J]. Pharmacog Mag, 2013, 9(34):114-119.